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1

GABA-A agonists and GABA uptake inhibitors: Structure-activity relationships

Erik Falch, Orla M. Larsson, Arne Schousboe, Povl Krogsgaard-Larsen

Journal:

Drug Development Research

Year:

1990

Language:

english

File:

PDF, 1.24 MB

english, 1990

2

Selective inhibitors of GABA uptake: synthesis and molecular pharmacology of 4-N-methylamino-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-ol analogues

Rasmus P. Clausen, Ejner K. Moltzen, Jens Perregaard, Sibylle M. Lenz, Connie Sanchez, Erik Falch, Bente Frølund, Tina Bolvig, Alan Sarup, Orla M. Larsson, Arne Schousboe, Povl Krogsgaard-Larsen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 417 KB

english, 2005

3

Inhibition of the betaine-GABA transporter (mGAT2/BGT-1) modulates spontaneous electrographic bursting in the medial entorhinal cortex (mEC)

Misty D. Smith, Gerald W. Saunders, Rasmus P. Clausen, Bente Frǿlund, Povl Krogsgaard-Larsen, Orla M. Larsson, Arne Schousboe, Karen S. Wilcox, H. Steve White

Journal:

Epilepsy Research

Year:

2008

Language:

english

File:

PDF, 786 KB

english, 2008

4

GABA uptake inhibitors: relevance to antiepileptic drug research

Povl Krogsgaard-Larsen, Erik Falch, Orla M. Larsson, Arne Schousboe

Journal:

Epilepsy Research

Year:

1987

Language:

english

File:

PDF, 1.40 MB

english, 1987

5

Anticonvulsant activity of intracerebroventricularly administered glial GABA uptake inhibitors and other GABAmimetics in chemical seizure models

Susan F. Gonsalves, Bonnie Twitchell, Robert E. Harbaugh, Povl Krogsgaard-Larsen, Arne Schousboe

Journal:

Epilepsy Research

Year:

1989

Language:

english

File:

PDF, 835 KB

english, 1989

6

Pharmacological and functional characterization of excitatory amino acid mediated cytotoxicity in cerebral cortical neurons

Arne Schousboe, Aase Frandsen, P. Krogsgaard-Larsen

Journal:

Cell Biology and Toxicology

Year:

1992

Language:

english

File:

PDF, 514 KB

english, 1992

7

Baclofen-induced, calcium-dependent stimulation of in vivo release ofd-[3H]aspartate from rat hippocampus monitored by intracerebral microdialysis

Elsebet Ø. Nielsen, Marianne Aarslew-Jensen, Nils Henrik Diemer, Povl Krogsgaard-Larsen, Arne Schousboe

Journal:

Neurochemical Research

Year:

1989

Language:

english

File:

PDF, 591 KB

english, 1989

8

Excitatory Amino Acids: Studies on the Biochemical and Chemical Stability of Ibotenic Acid and Related Compounds

Elsebet Ø. Nielsen, Arne Schousboe, Steen H. Hansen, Povl Krogsgaard-Larsen

Journal:

Journal of Neurochemistry

Year:

1985

Language:

english

File:

PDF, 704 KB

english, 1985

9

Novel Glutamate Receptor Antagonists Selectively Protect Against Kainic Acid Neurotoxicity in Cultured Cerebral Cortex Neurons

Aase Frandsen, Povl Krogsgaard-Larsen, Arne Schousboe

Journal:

Journal of Neurochemistry

Year:

1990

Language:

english

File:

PDF, 368 KB

english, 1990

10

Synaptic and extrasynaptic GABA transporters as targets for anti-epileptic drugs

Karsten K. Madsen, Rasmus P. Clausen, Orla M. Larsson, Povl Krogsgaard-Larsen, Arne Schousboe, H. Steve White

Journal:

Journal of Neurochemistry

Year:

2009

Language:

english

File:

PDF, 273 KB

english, 2009

11

10.1038/15525

Fugger, Lars, Madsen, Lars S., Andersson, Ellen Christina, Jansson, Liselotte, Krogsgaard, Michelle, Andersen, Claus B., Engberg, Jan, Strominger, Jack L., Svejgaard, Arne, Hjorth, Jens Peter, Holmdah

Journal:

Nature Genetics

Year:

1999

Language:

english

File:

PDF, 1.06 MB

english, 1999

12

Action of bicyclic isoxazole GABA analogues on GABA transporters and its relation to anticonvulsant activity

Tina Bolvig, Orla M Larsson, Darryl S Pickering, Nathan Nelson, Erik Falch, Povl Krogsgaard-Larsen, Arne Schousboe

Journal:

European Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 151 KB

english, 1999

13

The Effect of Intravenously Injected Reserpine on Blood Pressure, Renal Function and Sodium Excretion

ARNE R. KROGSGAARD

Journal:

Journal of Internal Medicine

Year:

1956

Language:

english

File:

PDF, 562 KB

english, 1956

14

The Effect of Reserpine on the Electrolyte and Fluid Balance in Man

ARNE R. KROGSGAARD

Journal:

Journal of Internal Medicine

Year:

1957

Language:

english

File:

PDF, 385 KB

english, 1957

15

Hypotensive Effect of Reserpine Compared with Phenobarbital and Placebo

ARNE R. KROGSGAARD

Journal:

Journal of Internal Medicine

Year:

1957

Language:

english

File:

PDF, 397 KB

english, 1957

16

Reserpine and Gastric Secretion in Man

ARNE R. KROGSGAARD

Journal:

Journal of Internal Medicine

Year:

1957

Language:

english

File:

PDF, 562 KB

english, 1957

17

Side-Effects of Reserpine in the Treatment of Essential Hypertension : With Special Reference to Weight Gain and Mental Depression

ARNE R. KROGSGAARD

Journal:

Journal of Internal Medicine

Year:

1958

Language:

english

File:

PDF, 680 KB

english, 1958

18

The Rôle of Reserpine in Essential Hypertension when Used alone or Combined with Hydralazine

ARNE R. KROGSGAARD

Journal:

Journal of Internal Medicine

Year:

1958

Language:

english

File:

PDF, 968 KB

english, 1958

19

Hydralazine in Arterial Hypertension : Randomized Double-Blind Comparison of Conventional/Slow-Release Formulation and of b.i.d. Iq.i.d. Dosage Regimens

Karl Wulff, Kristina Lenz, Arne R. Krogsgaard, Birgit Hoist

Journal:

Journal of Internal Medicine

Year:

1980

Language:

english

File:

PDF, 469 KB

english, 1980

20

Emergency Treatment of Severe Hypertension Evaluated in a Randomized Study : Effect of Rest and Furosemide and a Randomized Evaluation of Chlorpromazine, Dihydralazine and Diazoxide Danish Multicenter Study

Poul Ebbe Nielsen, Arne Krogsgaard, Allan McNair, Tage Hilden

Journal:

Journal of Internal Medicine

Year:

1980

Language:

english

File:

PDF, 564 KB

english, 1980

21

CEREBRAL SYMPTOMS AND BLOOD PRESSURE DURING PARENTERAL ADMINISTRATION OF CHLORPROMAZINE, DIHYDRALAZINE AND DIAZOXIDE. DANISH MULTICENTER STUDY ON ACUTE SEVERE HYPERTENSION.

Arne R. Krogsgaard, Tage Hilden, Allan McNair, Poul Ebbe Nielsen

Journal:

Journal of Internal Medicine

Year:

1984

Language:

english

File:

PDF, 344 KB

english, 1984

22

HAEMODYNAMIC EFFECTS OF CIGARETTE SMOKING BEFORE AND DURING LONG-TERM NON-SELECTIVE AND SELECTIVE BETA-ADRENERGIC BLOCKADE IN PATIENTS WITH ARTERIAL HYPERTENSION.

Mogens Tangø, Arne R. Krogsgaard, Jens Trap-Jensen, Jørgen Schläger

Journal:

Journal of Internal Medicine

Year:

1985

Language:

english

File:

PDF, 201 KB

english, 1985

23

REVERSIBILITY OF CEREBRAL SYMPTOMS IN SEVERE HYPERTENSION IN RELATION TO ACUTE ANTIHYPERTENSIVE THERAPY DANISH MULTICENTER STUDY

Allan McNair, Arne R. Krogsgaard, Tage Hilden, Poul Ebbe Nielsen

Journal:

Journal of Internal Medicine

Year:

1985

Language:

english

File:

PDF, 215 KB

english, 1985

24

Severe Hypertension with Cerebral Symptoms Treated with Furosemide, Fractionated Diazoxide or Dihydralazine : Danish Multicenter Study

ALLAN McNAIR, ARNE R. KROGSGAARD, TAGE HILDEN, POUL EBBE NIELSEN

Journal:

Journal of Internal Medicine

Year:

1986

Language:

english

File:

PDF, 543 KB

english, 1986

25

Reversibility of Cerebral Symptoms in Severe Hypertension in Relation to Acute Antihypertensive Therapy : Danish Multicenter Study

ARNE R. KROGSGAARD, ALLAN McNAIR, TAGE HILDEN, POUL EBBE NIELSEN

Journal:

Journal of Internal Medicine

Year:

1986

Language:

english

File:

PDF, 413 KB

english, 1986

26

REVERSIBILITY OF HYPERTENSIVE FUNDUS CHANGES DURING DRUG TREATMENT

Erik Godtfredsen, Arne R. Krogsgaard

Journal:

Acta Ophthalmologica (Blackwell)

Year:

1958

Language:

english

File:

PDF, 283 KB

english, 1958

27

Variations in the kinetic pattern of astrocytic γ-aminobutyric acid uptake when inhibited by different barbiturates

Orla M. Larsson, Arne Schousboe, Povl Krogsgaard-Larsen, Leif Hertz

Journal:

Biochemical Pharmacology

Year:

1982

Language:

english

File:

PDF, 251 KB

english, 1982

28

Anticonvulsant activity of the glial GABA uptake inhibitor, THAO, in chemical seizures

Susan F. Gonsalves, Bonnie Twitchell, Robert E. Harbaugh, Povl Krogsgaard-Larsen, Arne Schousboe

Journal:

European Journal of Pharmacology

Year:

1989

Language:

english

File:

PDF, 346 KB

english, 1989

29

Anticonvulsant activity of the γ-aminobutyric acid uptake inhibitor N-4,4-diphenyl-3-butenyl-4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-ol

H.Steve White, Jason Hunt, Harold H. Wolf, Ewart A. Swinyard, Erik Falch, Povl Krogsgaard-Larsen, Arne Schousboe

Journal:

European Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 220 KB

english, 1993

30

Different characteristics of AMPA receptor agonists acting at AMPA receptors expressed in Xenopus oocytes

Philip Wahl, Ulf Madsen, Tue Banke, Povl Krogsgaard-Larsen, Arne Schousboe

Journal:

European Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 766 KB

english, 1996

31

A novel selective γ-aminobutyric acid transport inhibitor demonstrates a functional role for GABA transporter subtype GAT2/BGT-1 in the CNS

Rasmus P. Clausen, Bente Frølund, Orla M. Larsson, Arne Schousboe, Povl Krogsgaard-Larsen, H. Steve White

Journal:

Neurochemistry International

Year:

2006

Language:

english

File:

PDF, 231 KB

english, 2006

32

Effects of 3-hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazol (exo-THPO) and its N-substituted analogs on GABA transport in cultured neurons and astrocytes and by the four cloned mouse GABA transporters

Alan Sarup, Orla Miller Larsson, Tina Bolvig, Bente Frølund, Povl Krogsgaard-Larsen, Arne Schousboe

Journal:

Neurochemistry International

Year:

2003

Language:

english

File:

PDF, 120 KB

english, 2003

33

Inhibition of the high-affinity, net uptake of GABA into cultured astrocytes by β-proline, nipecotic acid and other compounds

Arne Schousboe, Povl Krogsgaard-Larsen, Gerd Svenneby, Leif Hertz

Journal:

Year:

1978

Language:

english

File:

PDF, 250 KB

english, 1978

34

Differential effects of nipecotic acid and 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-ol on extracellular γ-aminobutyrate levels in rat thalamus

Gabor Juhász, Katalin A Kékesi, Gabriella Nyitrai, Arpád Dobolyi, Povl Krogsgaard-Larsen, Arne Schousboe

Journal:

European Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 237 KB

english, 1997

35

Selective mGAT2 (BGT-1) GABA Uptake Inhibitors: Design, Synthesis, and Pharmacological Characterization

Vogensen, Stine B., Jørgensen, Lars, Madsen, Karsten K., Borkar, Nrupa, Wellendorph, Petrine, Skovgaard-Petersen, Jonas, Schousboe, Arne, White, H. Steve, Krogsgaard-Larsen, Povl, Clausen, Rasmus P.

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 282 KB

english, 2013

36

GABAA Receptor Agonists, Partial Agonists, and Antagonists. Design and Therapeutic Prospects

Krogsgaard-Larsen, Povl, Froelund, Bente, Joergensen, Flemming S., Schousboe, Arne

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 3.30 MB

english, 1994

37

Structure-Activity Relationships of Selective GABA Uptake Inhibitors

Hog, Signe, Greenwood, Jeremy, Madsen, Karsten, Larsson, Orla, Frolund, Bente, Schousboe, Arne, Krogsgaard-Larsen, Povl, Clausen, Rasmus

Journal:

Current Topics in Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 180 KB

english, 2006

38

Treatment Of Severe Hypertension Using Chlorpromazine

Poul Ebbe Nielsen, Allan McNair, Arne R. Krogsgaard and Tage Hilden

Journal:

The British Medical Journal

Year:

1980

Language:

english

File:

PDF, 753 KB

english, 1980

39

Excitatory amino acid research in Alzheimer's disease: enhancement and blockade of receptor functions

Krogsgaard-Larsen, Povl, Wahl, Philip, Schousboe, Arne, Madsen, Ulf, Hansen, Jan J.

Journal:

Biochemical Society Transactions

Year:

1993

Language:

english

File:

PDF, 443 KB

english, 1993

40

LOW SERUM POTASSIUM LEVEL IN SEVERE HYPERTENSION

Hilden, Tage, Krogsgaard, Arne R.

Journal:

The American Journal of the Medical Sciences

Year:

1958

File:

PDF, 1.46 MB

1958